{"id":94089,"date":"2025-05-19T10:12:06","date_gmt":"2025-05-19T10:12:06","guid":{"rendered":"https:\/\/ekamu.net\/?p=94089"},"modified":"2025-05-19T10:12:06","modified_gmt":"2025-05-19T10:12:06","slug":"diyabet-ve-yaslilikta-ortaya-cikan-gorme-sorunlari-icin-umut-verici-cozum-rna-terapisi","status":"publish","type":"post","link":"https:\/\/ekamu.net\/index.php\/2025\/05\/19\/diyabet-ve-yaslilikta-ortaya-cikan-gorme-sorunlari-icin-umut-verici-cozum-rna-terapisi\/","title":{"rendered":"Diyabet ve ya\u015fl\u0131l\u0131kta ortaya \u00e7\u0131kan g\u00f6rme sorunlar\u0131 i\u00e7in umut verici \u00e7\u00f6z\u00fcm: RNA terapisi"},"content":{"rendered":"

<\/span> G\u00f6z sa\u011fl\u0131\u011f\u0131 i\u00e7in umut vaat eden yeni bir tedavi y\u00f6ntemi ortaya \u00e7\u0131kt\u0131. Diyabet ve ya\u015fl\u0131l\u0131k<\/strong> gibi nedenlerle olu\u015fan g\u00f6rme kay\u0131plar\u0131n\u0131n<\/strong> en b\u00fcy\u00fck nedenlerinden biri olan damar hastal\u0131klar\u0131na kar\u015f\u0131 geli\u015ftirilen RNA terapisi<\/strong>, geleneksel tedavi y\u00f6ntemlerine g\u00f6re daha etkili ve uzun s\u00fcreli bir \u00e7\u00f6z\u00fcm sunuyor. <\/figure>\n

RNA terapisi, g\u00f6z hastal\u0131klar\u0131nda yeni bir \u00e7a\u011f a\u00e7\u0131yor: \u0130nvaziv enjeksiyonlara veda<\/b><\/p>\n

Diyabetik retinopati, d\u00fcnya \u00e7ap\u0131nda diyabetlilerin %22’sini <\/strong>etkileyen g\u00f6rmeyi tehdit eden bir komplikasyondur. Ancak tedavisi olduk\u00e7a s\u0131n\u0131rl\u0131d\u0131r ve en etkili tedavilerden biri, g\u00f6rmeyi stabilize etmek ve iyile\u015ftirmek i\u00e7in g\u00f6ze d\u00fczenli olarak ila\u00e7 enjeksiyonlar\u0131d\u0131r.<\/strong> Yak\u0131n bir zamanda Avustralya G\u00f6z Ara\u015ft\u0131rmalar\u0131 Merkezi (CERA) ve Melbourne \u00dcniversitesi liderli\u011finde ger\u00e7ekle\u015ftirilen yeni bir ara\u015ft\u0131rma ise milyonlarca insan\u0131 etkileyen bu g\u00f6z hastal\u0131klar\u0131n\u0131n tedavisinde d\u00fczenli g\u00f6z enjeksiyonlar\u0131n\u0131n yerini alabilecek, bir ki\u015finin RNA’s\u0131n\u0131n d\u00fczenlenmesi<\/strong> olan yeni nesil bir gen terapisi geli\u015ftirdi.<\/p>\n

<\/span> RNA d\u00fczenleme teknolojisi sayesinde geli\u015ftirilen yeni bir gen terapisi, g\u00f6z hastal\u0131klar\u0131n\u0131n tedavisinde \u00e7\u0131\u011f\u0131r a\u00e7\u0131c\u0131 bir geli\u015fme olarak de\u011ferlendiriliyor. VEGF proteininina\u015f\u0131r\u0131 \u00fcretimiyle ortaya \u00e7\u0131kan diyabetik retinopati<\/strong> ve ya\u015fa ba\u011fl\u0131 mak\u00fcla dejenerasyonu<\/strong> gibi hastal\u0131klarda, CRISPR-Cas13 gibi RNA d\u00fczenleme ara\u00e7lar\u0131 kullan\u0131larak VEGF \u00fcretimini bast\u0131rmak<\/strong> hedefleniyor. Bu sayede, hastal\u0131\u011f\u0131n ilerlemesi yava\u015flat\u0131l\u0131yor ve g\u00f6rme kayb\u0131 \u00f6nleniyor. <\/figure>\n

CERA’da doktora \u00f6\u011frencisi ve \u00e7al\u0131\u015fman\u0131n ba\u015f yazar\u0131 olan Satheesh Kumar, ara\u015ft\u0131rma ile ilgili yapt\u0131\u011f\u0131 a\u00e7\u0131klamalarda “RNA d\u00fczenlemesi, h\u00fccrelerin DNA’lar\u0131n\u0131 kal\u0131c\u0131 olarak de\u011fi\u015ftirmeden, h\u00fccrelerin davran\u0131\u015f bi\u00e7imini etkileyen genetik talimatlar\u0131 de\u011fi\u015ftirmemizi sa\u011fl\u0131yor.”<\/em> ifadelerine yer verdi.<\/p>\n\n

https:\/\/www.youtube.com\/embed\/0JXZzrHL2Ho<\/span><\/p>\n

Kaynak :\u00a0https:\/\/www.donanimhaber.com\/gorme-sorunlari-icin-umut-vaat-eden-cozum-rna-terapisi–184045<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

G\u00f6z sa\u011fl\u0131\u011f\u0131 i\u00e7in umut vaat eden yeni bir tedavi y\u00f6ntemi ortaya \u00e7\u0131kt\u0131. Diyabet ve ya\u015fl\u0131l\u0131k gibi nedenlerle olu\u015fan g\u00f6rme kay\u0131plar\u0131n\u0131n en b\u00fcy\u00fck nedenlerinden biri olan damar hastal\u0131klar\u0131na kar\u015f\u0131 geli\u015ftirilen RNA terapisi, geleneksel tedavi …<\/p>\n","protected":false},"author":1,"featured_media":94090,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[765,5592,102],"class_list":["post-94089","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-teknoloji","tag-goz","tag-rna","tag-tedavi"],"_links":{"self":[{"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/posts\/94089","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/comments?post=94089"}],"version-history":[{"count":1,"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/posts\/94089\/revisions"}],"predecessor-version":[{"id":94093,"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/posts\/94089\/revisions\/94093"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/media\/94090"}],"wp:attachment":[{"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/media?parent=94089"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/categories?post=94089"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/tags?post=94089"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}