{"id":97660,"date":"2025-05-25T07:00:18","date_gmt":"2025-05-25T07:00:18","guid":{"rendered":"https:\/\/ekamu.net\/?p=97660"},"modified":"2025-05-25T07:00:18","modified_gmt":"2025-05-25T07:00:18","slug":"bilim-dunyasinda-ilginc-gelisme-sivrisinekler-asi-dagitim-araci-olarak-kullanilabilir","status":"publish","type":"post","link":"https:\/\/ekamu.net\/index.php\/2025\/05\/25\/bilim-dunyasinda-ilginc-gelisme-sivrisinekler-asi-dagitim-araci-olarak-kullanilabilir\/","title":{"rendered":"Bilim d\u00fcnyas\u0131nda ilgin\u00e7 geli\u015fme: Sivrisinekler a\u015f\u0131 da\u011f\u0131t\u0131m arac\u0131 olarak kullan\u0131labilir"},"content":{"rendered":"

<\/span> Londra Hijyen ve Tropikal T\u0131p Okulu ara\u015ft\u0131rmac\u0131lar\u0131, sivrisinekleri <\/strong>kullanarak a\u015f\u0131 da\u011f\u0131t\u0131m\u0131nda \u00e7\u0131\u011f\u0131r a\u00e7an bir ba\u015far\u0131ya imza att\u0131. Geleneksel y\u00f6ntemlerin aksine, sivrisinek \u0131s\u0131r\u0131\u011f\u0131 yoluyla uygulanan bu yenilik\u00e7i a\u015f\u0131lama tekni\u011fi,<\/strong> klinik denemelerde %90’a varan etkinlik g\u00f6sterdi. Bu geli\u015fme, \u00f6zellikle s\u0131tma <\/strong>gibi tropical hastal\u0131klarla m\u00fccadelede yeni bir d\u00f6nemin kap\u0131lar\u0131n\u0131 aral\u0131yor. <\/figure>\n

S\u0131tma parazitinin genetik modifikasyonu ile yeni bir d\u00f6nem ba\u015flayabilir<\/b><\/p>\n

Ara\u015ft\u0131rma ekibi, genellikle hastal\u0131k ta\u015f\u0131y\u0131c\u0131s\u0131 olarak bilinen sivrisinekleri yararl\u0131 bir ama\u00e7 i\u00e7in kullanmaya odakland\u0131. \u00c7al\u0131\u015fman\u0131n merkezinde, s\u0131tman\u0131n ana nedeni olan Plasmodium falciparum<\/strong> parazitinin genetik olarak modifiye edilmi\u015f versiyonu yer al\u0131yor. GA2 ad\u0131 verilen bu modifiye parazit, normal s\u0131tma parazitinden farkl\u0131 olarak hastal\u0131\u011fa neden olmak yerine ba\u011f\u0131\u015f\u0131kl\u0131k sistemini g\u00fc\u00e7lendiriyor<\/strong>.<\/p>\n

<\/span> Bilim insanlar\u0131, 43 g\u00f6n\u00fcll\u00fc \u00fczerinde ger\u00e7ekle\u015ftirdilen klinik denemelerde iki a\u015famal\u0131 bir test protokol\u00fc uygulad\u0131. \u0130lk a\u015famada, 20 kat\u0131l\u0131mc\u0131 modifiye parazit ta\u015f\u0131yan sivrisineklerin \u0131s\u0131r\u0131klar\u0131na maruz b\u0131rak\u0131ld\u0131 ve hi\u00e7bir kat\u0131l\u0131mc\u0131da kan enfeksiyonu g\u00f6r\u00fclmedi. \u0130kinci a\u015famada ise 23 g\u00f6n\u00fcll\u00fc, 28 g\u00fcn arayla \u00fc\u00e7 kez sivrisinek \u0131s\u0131r\u0131\u011f\u0131 ald\u0131. Bu gruptan GA2 paraziti ile a\u015f\u0131lananlar\u0131n %89’u<\/strong>, daha sonraki s\u0131tma maruziyetine kar\u015f\u0131 ba\u015far\u0131yla korundu. <\/figure>\n

Ancak bu yenilik\u00e7i yakla\u015f\u0131m\u0131n yayg\u0131n kullan\u0131ma ge\u00e7meden \u00f6nce a\u015fmas\u0131 gereken baz\u0131 zorluklar bulunuyor. Laboratuvar ortam\u0131nda insan kan h\u00fccreleri \u00fczerinde k\u00fclt\u00fcrlenen parazitlerin sivrisineklere aktar\u0131lmas\u0131 ve bu sivrisineklerin a\u015f\u0131 ta\u015f\u0131y\u0131c\u0131s\u0131 olarak haz\u0131r hale gelmesi yakla\u015f\u0131k iki hafta <\/strong>s\u00fcr\u00fcyor. Bu durum, b\u00fcy\u00fck \u00f6l\u00e7ekli uygulamalar\u0131 zorla\u015ft\u0131r\u0131yor.<\/p>\n\n

<\/span><\/p>\n

Kaynak :\u00a0https:\/\/www.donanimhaber.com\/sivrisinekler-cok-yakinda-asi-dagitim-araci-olarak-kullanilabilir–184509<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Londra Hijyen ve Tropikal T\u0131p Okulu ara\u015ft\u0131rmac\u0131lar\u0131, sivrisinekleri kullanarak a\u015f\u0131 da\u011f\u0131t\u0131m\u0131nda \u00e7\u0131\u011f\u0131r a\u00e7an bir ba\u015far\u0131ya imza att\u0131. Geleneksel y\u00f6ntemlerin aksine, sivrisinek \u0131s\u0131r\u0131\u011f\u0131 yoluyla uygulanan bu yenilik\u00e7i a\u015f\u0131lama tekni\u011fi, klinik denemelerde …<\/p>\n","protected":false},"author":1,"featured_media":97661,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[5818,5819,5820],"class_list":["post-97660","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-teknoloji","tag-parazit","tag-sivrisinek","tag-sitma"],"_links":{"self":[{"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/posts\/97660","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/comments?post=97660"}],"version-history":[{"count":1,"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/posts\/97660\/revisions"}],"predecessor-version":[{"id":97664,"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/posts\/97660\/revisions\/97664"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/media\/97661"}],"wp:attachment":[{"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/media?parent=97660"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/categories?post=97660"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ekamu.net\/index.php\/wp-json\/wp\/v2\/tags?post=97660"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}